Treatment

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  The Kindest Cut

  Before undergoing surgery, cancer patients should look for experienced surgeons, get second opinions and ask about the risks and benefits.

  by Stephen Ornes

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  Going Off-Label

  Physicians are legally permitted to prescribe drugs approved for one purpose to be used for another, a practice called off-label prescribing. The rise of targeted therapies and immunotherapies is creating new challenges for navigating off-label options.

  by Kate Yandell

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  Immunotherapy Combinations

  Researchers are combining immunotherapies with each other and with other treatments in hopes that a larger proportion of patients will have long-term benefits.

  by Kate Yandell

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  From the Editor-in-Chief

  Palliative Care: Putting a Cloak on Cancer

  Patients should have access to this vital and emerging medical specialty.

  by William G. Nelson, MD, PhD

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  Forward Look

  Weighing Tumor Testing

  New sequencing tests bring new questions.

  by Kate Yandell

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  Forward Look

  Making Treatment Decisions

  Personal goals come into play for patients with advanced cancer.

  by Kendall K. Morgan

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  Forward Look

  Advances in Treating Non–Small Cell Lung Cancer

  Expanded approvals in 2016 increase options.

  by Jennifer L.W. Fink

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  Forward Look

  Cancer Cells Can Change as They Grow and Spread

  Studies suggest metastases may respond to different drugs than the primary tumor.

  by Chris Palmer

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  Seeking a Second Opinion

  Another perspective on your disease may help you find the best cancer care.

  by Stephen Ornes

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  From the Editor-in-Chief

  Cancer and the Microbiome

  Altering the gut microbiota and microbiome could become a strategy for cancer prevention and treatment.

  by William G. Nelson, MD, PhD