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What Do Clinical Trial Endpoints Really Measure?A study investigates whether a commonly used clinical trial endpoint, progression-free survival, can be used to predict quality of life.
by Jon Kelvey
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Treating Breast Cancer in MenHormone therapy may lengthen life in men with hormone-related breast cancer, but this treatment is prescribed less frequently for men than for women.
by Marilyn Fenichel
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Forward Look
Treating Head and Neck Skin CancersA study suggests high-risk patients do not need chemotherapy.
by Stephen Ornes
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Forward Look
In Women, Lung Cancer Rates Are Rising WorldwideLung cancer deaths are set to surpass breast cancer deaths in many regions.
by Cameron Walker
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Forward Look
Breaking Down Breakthrough Cancer TherapiesDrugs approved through this pathway may have limited evidence.
by Lindsey Konkel
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Tomorrow’s TrialsNew tools are being integrated into the research process to ease patients' access to clinical trials and improve their experience.
by Bradley Jones
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Forward Look
What’s Next? Winter 2018/2019Off-the-shelf equivalents to CAR-T cell therapy are emerging.
by Bradley Jones
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From the Editor-in-Chief
Improving Health After TreatmentThe U.S. health care system must adapt to the needs of cancer survivors.
by William G. Nelson, MD, PhD
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Getting a Read on CancerCancer patients are increasingly receiving treatments guided by the molecular characteristics of their cancer cells. But patients may have unequal access to testing and targeted therapies.
by Kate Yandell
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Forward Look
A Matter of AgeCell and molecular biologist Ashani Weeraratna discusses how older patients respond to immunotherapy.
by Sue Rochman
A new treatment for people with hormone receptor-positive, HER2-negative disease blocks multiple proteins in a key pathway for treatment resistance.
by Ashley P. Taylor
Amanda Peet Discusses Her Lobular Breast Cancer DiagnosisThe ‘Your Friends & Neighbors’ actress explains how her diagnosis challenged many of her assumptions about breast cancer.
by Darlene Dobkowski
Why I Participated in a Clinical TrialWhen doctors told Yvonne McLean Florence she was eligible to participate in a research trial testing an experimental drug, she joined. She wants more people to have the same opportunity.
by Yvonne McLean Florence
Targeted Therapy Improves Pancreatic Cancer SurvivalA recently approved drug that targets RAS proteins meaningfully improves outcomes for people with this difficult-to-treat cancer.
by Sandra Gordon
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AACR OMB Statement and Call to ActionThe AACR is deeply concerned that proposed OMB regulations would disrupt federal research grant giving, severely weakening a program that has supported American medical innovation for decades.
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AACR Cancer Disparities Progress ReportThe AACR Cancer Disparities Progress Report 2026 highlights recent progress in reducing cancer disparities and emphasizes the continued need for transformative research.
Cancer Research at a Crossroads
