Physicians are legally permitted to prescribe drugs approved for one purpose to be used for another, a practice called off-label prescribing. The rise of targeted therapies and immunotherapies is creating new challenges for navigating off-label options.

by Kate Yandell

Karyn Marshall, James Gathright, Catherine Hargrove.

More focused efforts aim to increase the number and type of participants in research studies. One goal is for study participants to be more like the patients who will take the drug if it is approved.

by Sue Rochman

Survivor Profile

An acute myeloid leukemia survivor and former TV news reporter finds a new reason to help others improve their health.

by Jennifer Walker

Another perspective on your disease may help you find the best cancer care.

by Stephen Ornes

Yesterday & Today

Michael Landon, best known for his roles on Little House on the Prairie and Bonanza, created and starred in programs that portrayed family values with authenticity and humor.

by Marci A. Landsmann

Morgan Bolt, Esther Brandon, Randy Lopez.

For a patient with advanced cancer, how important is screening for other types of cancer?

by Ide Mills

Darla Moore, Janiela Roachford, Roseanne Venturino.

Conflicting and changing cancer screening guidelines have led to uncertainty and controversy. Can screening recommendations tailored for groups or individuals enhance benefits and reduce harms?

by Kate Yandell