1960: Peter Nowell and David Hungerford report an abnormally small chromosome in cells taken from patients with chronic myelogenous leukemia (CML). The dwarfed version of chromosome 22 will later be dubbed the Philadelphia chromosome.
1972: Janet Rowley discovers the 9;22 translocation: a broken piece of chromosome 22 attached to chromosome 9.
Less than three years after the beginning of the first clinical study and in near record time, the U.S. Food and Drug Administration approves Gleevec.
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